Annotation Detail

Information
Associated Genes
CYP21A2
Associated Variants
CYP21A2 p.Ile173Asn (p.I173N) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Ile173Asn (p.I173N) ( ENST00000435122.3, ENST00000644719.2 )
Associated Disease
Chronic active hepatitis
Source Database
DisGeNET
Description
Adult young women with CAH: three with the salt-wasting form and four patients with simple virilizing CAH due to severe homozygous or compound heterozygous mutations of the CYP21B gene (deletions, I172N in exon 4 and nt656A/C-->G in intron 2) who wished to become pregnant.
Pubmed
15136096
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0423449320445273
Year of publication
2004
Drugs