Annotation Detail

Information
Associated Genes
CYP21A2
Associated Variants
CYP21A2 p.Val282Met (p.V282M) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Met (p.V282M) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
Associated Disease
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency
Source Database
DisGeNET
Description
To report a first case of 21-hydroxylase deficiency associated with a new genotype determined by V281+I172N/V281L mutations of the CYP21A2 gene.
Pubmed
18028896
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.302953446367544
Year of publication
2007
Drugs