Annotation Detail

Information
Associated Genes
CYP21A2
Associated Variants
CYP21A2 p.Val282Met (p.V282M) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Pro454Ser (p.P454S) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Met (p.V282M) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Val282Leu (p.V282L) ( ENST00000435122.3, ENST00000644719.2 )
CYP21A2 p.Pro454Ser (p.P454S) ( ENST00000435122.3, ENST00000644719.2 )
Associated Disease
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency
Source Database
DisGeNET
Description
Phenotype-genotype correlations of 13 rare CYP21A2 mutations detected in 46 patients affected with 21-hydroxylase deficiency and in one carrier.
Pubmed
20080860
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.302953446367544
Year of publication
2010
Drugs