Annotation Detail
Information
- Associated Genes
- SOAT1
- Associated Variants
-
SOAT1 MUTATION
SOAT1 MUTATION - Associated Disease
- liver carcinoma
- Source Database
- DisGeNET
- Description
- We also found that inhibition of SPTBN1 or SMAD3 upregulated STAT3 promoter activity in HCC cell-lines, which is dependent upon the cAMP-response element (CRE) and STAT-binding element (SBE) sites of the STAT3 promoter.
- Pubmed
- 25096061
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
Drugs