Annotation Detail

Information
Associated Genes
MAPT
Associated Variants
MAPT p.Asn671Lys (p.N671K) ( ENST00000334239.12, ENST00000574436.5, ENST00000415613.6, ENST00000344290.10, ENST00000262410.10, ENST00000446361.7, ENST00000431008.7, ENST00000535772.6, ENST00000420682.7, ENST00000351559.10, ENST00000571987.5, ENST00000680674.1 )
MAPT p.Asn671Lys (p.N671K) ( ENST00000262410.10, ENST00000446361.7, ENST00000351559.10, ENST00000344290.10, ENST00000334239.12, ENST00000415613.6, ENST00000420682.7, ENST00000431008.7, ENST00000535772.6, ENST00000571987.5, ENST00000574436.5, ENST00000680674.1 )
Associated Disease
Pallidopontonigral degeneration
Source Database
DisGeNET
Description
Physiologic assessment of autonomic dysfunction in pallidopontonigral degeneration with N279K mutation in the tau gene on chromosome 17.
Pubmed
12492138
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2002
Drugs