Annotation Detail

Information
Associated Genes
EBI3
Associated Variants
EBI3 MUTATION
EBI3 MUTATION
Associated Disease
Precursor Cell Lymphoblastic Leukemia Lymphoma
Source Database
DisGeNET
Description
Frequent mutations in cytokine receptor and Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling pathways led us to hypothesize that ETP-ALL is dependent on JAK/STAT signaling.
Pubmed
25645356
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00162865123248182
Drugs