Annotation Detail
Information
- Associated Genes
- BCR
- Associated Variants
-
BCR MUTATION
BCR MUTATION - Associated Disease
- Precursor Cell Lymphoblastic Leukemia Lymphoma
- Source Database
- DisGeNET
- Description
- The presence of the Philadelphia chromosome causing the fusion between BCR to ABL1 in B cell precursor acute lymphoblastic leukemias (ALLs) was associated with a particularly bad prognosis, which has been markedly improved with the addition of imatinib to chemotherapy.
- Pubmed
- 24848770
- Section of the abstract supporting the evidence
- PURPOSE OF REVIEW
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,CTD_human,LHGDN
- DisGENET score for the Gene Disease association
- 0.140649445321431
Drugs