Annotation Detail
Information
- Associated Genes
- ATM
- Associated Variants
-
ATM MUTATION
ATM MUTATION - Associated Disease
- Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
- Source Database
- DisGeNET
- Description
- We conclude that CHK1 is critical for T-ALL proliferation and viability by downmodulating replication stress and preventing ATM/caspase-3-dependent cell death.
- Pubmed
- 25132270
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
Drugs