Annotation Detail

Information
Associated Genes
APP
Associated Variants
APP p.Ala713Thr (p.A713T) ( ENST00000346798.8, ENST00000348990.9, ENST00000354192.7, ENST00000357903.7, ENST00000358918.7, ENST00000359726.7, ENST00000439274.6, ENST00000440126.7 )
APP p.Ala713Thr (p.A713T) ( ENST00000346798.8, ENST00000348990.9, ENST00000354192.7, ENST00000357903.7, ENST00000358918.7, ENST00000359726.7, ENST00000439274.6, ENST00000440126.7 )
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
Homozygous carriers of APP A713T mutation in an autosomal dominant Alzheimer disease family.
Pubmed
25948718
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.600803934708039
Year of publication
2015
Drugs