Annotation Detail
Information
- Associated Genes
- PCSK9
- Associated Variants
-
PCSK9 MUTATION
PCSK9 MUTATION - Associated Disease
- coronary artery disease
- Source Database
- DisGeNET
- Description
- The L10 allele is associated with a reduced risk and severity of CAD, seemingly independently of its LDL-lowering effect, suggesting a direct effect of PCSK9 on atherogenesis.
- Pubmed
- 25239117
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD
- DisGENET score for the Gene Disease association
- 0.13035839840077
Drugs