Annotation Detail

Information
Associated Genes
HTR2C
Associated Variants
HTR2C p.Cys23= (p.C23=) ( ENST00000276198.6, ENST00000371950.3, ENST00000371951.5 )
HTR2C p.Ser23Cys (p.S23C) ( ENST00000276198.6, ENST00000371950.3, ENST00000371951.5 )
Associated Disease
Pituitary Diseases
Source Database
DisGeNET
Description
Previously we have shown that a functional nonsynonymous single nucleotide polymorphism (rs6318) of the 5HTR2C gene located on the X-chromosome is associated with hypothalamic-pituitary-adrenal axis response to a stress recall task, and with endophenotypes associated with cardiovascular disease (CVD).
Pubmed
24386118
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2013
Drugs