Annotation Detail
Information
- Associated Genes
- NOS3
- Associated Variants
-
NOS3 MUTATION
NOS3 MUTATION - Associated Disease
- coronary artery disease
- Source Database
- DisGeNET
- Description
- Several studies have suggested that ALDH2 polymorphism plays an important role in the progress of CAD through multiple mechanisms, including the regulation of alcohol consumption, inflammation, endothelial progenitor cells, oxidative stress, asymmetric dimethylarginine, endothelial nitric oxide synthase, and other CAD-promoting factors.
- Pubmed
- 25263942
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.233686922404653
Drugs