Annotation Detail
Information
- Associated Genes
- HTR2A
- Associated Variants
-
HTR2A p.His452Tyr (p.H452Y)
(
ENST00000543956.5,
ENST00000542664.4 )
HTR2A p.His452Tyr (p.H452Y) ( ENST00000542664.4, ENST00000543956.5 ) - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Polymorphisms in the monoamine oxidase A (MAOA-LPR) and serotonin receptor 2A genes (rs6314) moderated the effect of food reinforcement on BMI, accounting for an additional 5-10% variance and revealed a potential role of the single nucleotide polymorphism, rs6314, in the serotonin 2A receptor as a differential susceptibility factor for obesity.
- Pubmed
- 23544600
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.134006694869653
- Year of publication
- 2013
Drugs