Annotation Detail
Information
- Associated Genes
- HTR1B
- Associated Variants
-
HTR1B p.Val287= (p.V287=)
(
ENST00000369947.5 )
HTR1B p.Val287= (p.V287=) ( ENST00000369947.5 ) - Associated Disease
- Single major depressive episode
- Source Database
- DisGeNET
- Description
- Exploratory analyses indicated an association of the genotype and allele frequencies of the h5-HTR(1B) G861C locus with a history of substance abuse disorder (chi(2) = 9.51, df = 2, p = 0.009; chi(2) = 7.31, df = 1, p = 0.007, respectively) and with a diagnosis of a major depressive episode (chi(2) = 6.83, df = 2, p = 0.033; chi(2) = 5.81, df = 1, p = 0.016, respectively).
- Pubmed
- 12496953
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2003
Drugs