Annotation Detail

Information
Associated Genes
DRD2
Associated Variants
DRD2 c.*52G>A ( ENST00000542968.5, ENST00000538967.5, ENST00000362072.8, ENST00000346454.7, ENST00000544518.5 )
DRD2 c.*52G>A ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
Associated Disease
Alcohol Withdrawal Seizures
Source Database
DisGeNET
Description
However, we found a significant interaction effect of the SLC6A4 promoter polymorphism (5-HTTLPR) and DRD2 exon 8 single nucleotide polymorphism rs6276 on AWS and/or DT history (P = 0.009), which became more significant after adjustment for lifetime maximum number of drinks consumed per 24 hours (P < 0.001).
Pubmed
20002020
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2010
Drugs