Annotation Detail
Information
- Associated Genes
- SHBG
- Associated Variants
-
SHBG p.Asp356Asn (p.D356N)
(
ENST00000570547.5,
ENST00000416273.7,
ENST00000380450.9,
ENST00000572182.5,
ENST00000572262.5,
ENST00000340624.9,
ENST00000575314.5,
ENST00000575903.5,
ENST00000574539.5,
ENST00000576478.5,
ENST00000441599.6,
ENST00000576728.5 )
SHBG p.Asp356Asn (p.D356N) ( ENST00000340624.9, ENST00000380450.9, ENST00000416273.7, ENST00000441599.6, ENST00000570547.5, ENST00000572182.5, ENST00000572262.5, ENST00000574539.5, ENST00000575314.5, ENST00000575903.5, ENST00000576478.5, ENST00000576728.5 ) - Associated Disease
- gallbladder carcinoma
- Source Database
- DisGeNET
- Description
- Among women taking oral contraceptives, the effect of SHBG Ex8 + 6 (rs6259) on gallbladder cancer (OR = 6.7, 95% CI = 2.2-20.5; P interaction = 0.001) and stones (OR = 2.3, 95% CI = 1.1-4.9; P-interaction = 0.05) was statistically significant.
- Pubmed
- 19168589
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2009
Drugs