Annotation Detail

Information
Associated Genes
SHBG
Associated Variants
SHBG p.Asp356Asn (p.D356N) ( ENST00000570547.5, ENST00000416273.7, ENST00000380450.9, ENST00000572182.5, ENST00000572262.5, ENST00000340624.9, ENST00000575314.5, ENST00000575903.5, ENST00000574539.5, ENST00000576478.5, ENST00000441599.6, ENST00000576728.5 )
SHBG p.Asp356Asn (p.D356N) ( ENST00000340624.9, ENST00000380450.9, ENST00000416273.7, ENST00000441599.6, ENST00000570547.5, ENST00000572182.5, ENST00000572262.5, ENST00000574539.5, ENST00000575314.5, ENST00000575903.5, ENST00000576478.5, ENST00000576728.5 )
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
Further, the relation between breast cancer risk and SHBG rs6259 was found to vary by body mass index (weight (kg)/height (m)(2)) (P for interaction = 0.003).
Pubmed
21454829
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0228883317781819
Year of publication
2011
Drugs