Annotation Detail
Information
- Associated Genes
- PCSK1
- Associated Variants
-
PCSK1 p.Ser690Thr (p.S690T)
(
ENST00000311106.8,
ENST00000508626.5 )
PCSK1 p.Ser690Thr (p.S690T) ( ENST00000311106.8, ENST00000508626.5 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- [Two loci (LARP6 and SGSM2) have not been previously related to metabolic traits, one (MADD) has been associated with fasting glucose, one (PCSK1) has been implicated in obesity, and four (TCF7L2, SLC30A8, VPS13C/C2CD4A/B, and ARAP1, formerly CENTD2) increase T2D risk.]
- Pubmed
- 21873549
- Original source reporting the Gene Disease association
- GAD
- DisGENET score for the Gene Disease association
- 0.0974594943365758
- Year of publication
- 2011
Drugs