Annotation Detail

Information
Associated Genes
KRAS
Associated Variants
KRAS c.*2626T>G ( ENST00000256078.10, ENST00000688940.1, ENST00000553788.6, ENST00000692768.1, ENST00000685328.1, ENST00000693229.1, ENST00000311936.8 )
KRAS c.*2626T>G ( ENST00000256078.10, ENST00000311936.8, ENST00000685328.1, ENST00000688940.1, ENST00000692768.1, ENST00000693229.1, ENST00000553788.6 )
Associated Disease
colorectal cancer
Source Database
DisGeNET
Description
Using site-specific homologous recombination, we inserted the rs61764370:T>G KRAS gene variant in the colorectal cancer cell line SW48 (SW48 +SNP) and assessed the cellular and biochemical phenotype.
Pubmed
24282149
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.16
Year of publication
2013
Drugs