Annotation Detail

Information
Associated Genes
SCNN1A
Associated Variants
SCNN1A p.Val173Ile (p.V173I) ( ENST00000396966.6, ENST00000228916.7, ENST00000543768.1, ENST00000360168.7 )
SCNN1A p.Phe120Leu (p.F120L) ( ENST00000228916.7, ENST00000396966.6, ENST00000360168.7, ENST00000543768.1 )
SCNN1A p.Val173Ile (p.V173I) ( ENST00000228916.7, ENST00000360168.7, ENST00000396966.6, ENST00000543768.1 )
SCNN1A p.Phe120Leu (p.F120L) ( ENST00000228916.7, ENST00000360168.7, ENST00000396966.6, ENST00000543768.1 )
Associated Disease
Bronchiectasis with or without elevated sweat chloride 2
Source Database
DisGeNET
Description
Mutations in the amiloride-sensitive epithelial sodium channel in patients with cystic fibrosis-like disease.
Pubmed
19462466
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.36
Year of publication
2009
Drugs