Annotation Detail

Information
Associated Genes
MSH3
Associated Variants
MSH3 MUTATION
MSH3 MUTATION
Associated Disease
Lubs X-linked mental retardation syndrome
Source Database
DisGeNET
Description
Complex duplication-inverted triplication-duplication (DUP-TRP/INV-DUP) rearrangements that contain breakpoint junctions within IRs have been recently associated with both MECP2 duplication syndrome (MIM#300260) and Pelizaeus-Merzbacher disease (PMD, MIM#312080).
Pubmed
25749076
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs