Annotation Detail

Information
Associated Genes
CACNA1C
Associated Variants
CACNA1C MUTATION
CACNA1C MUTATION
Associated Disease
Timothy syndrome
Source Database
DisGeNET
Description
Mutations in CACNA1C that increase current through the CaV1.2 L-type Ca2+ channel underlie rare forms of long QT syndrome (LQTS), and Timothy syndrome (TS).
Pubmed
25184293
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CLINVAR,CTD_human,MGD,ORPHANET,UNIPROT
DisGENET score for the Gene Disease association
0.566243163057847
Drugs