Annotation Detail
Information
- Associated Genes
- F5
- Associated Variants
-
F5 p.Gln534= (p.Q534=)
(
ENST00000367796.3,
ENST00000367797.9 )
F5 p.Arg534Gln (p.R534Q) ( ENST00000367796.3, ENST00000367797.9 ) - Associated Disease
- Deep thrombophlebitis
- Source Database
- DisGeNET
- Description
- Women carrying the factor V Leiden (F5 rs6025) polymorphism, or who had reduced sensitivity to activated protein C (aPC) in the absence of F5 rs6025, had increased risk for DVT, with unadjusted ORs 7.7 (95% CI 4.7-12.7) and 3.5 (95% CI 2.2-5.4), respectively.
- Pubmed
- 23015030
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00407162808120455
- Year of publication
- 2012
Drugs