Annotation Detail

Information
Associated Genes
LMNA
Associated Variants
LMNA p.Arg298Cys (p.R298C) ( ENST00000448611.6, ENST00000504687.7, ENST00000368300.9, ENST00000682650.1, ENST00000676385.2, ENST00000368299.7, ENST00000473598.6, ENST00000368297.5, ENST00000675667.1, ENST00000368301.6, ENST00000361308.9, ENST00000683032.1, ENST00000675939.1, ENST00000677389.1 )
LMNA p.Arg298Cys (p.R298C) ( ENST00000361308.9, ENST00000368297.5, ENST00000368299.7, ENST00000368300.9, ENST00000368301.6, ENST00000448611.6, ENST00000473598.6, ENST00000504687.7, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
Associated Disease
Charcot-Marie-Tooth disease
Source Database
DisGeNET
Description
Phenotypic variability in autosomal recessive axonal Charcot-Marie-Tooth disease due to the R298C mutation in lamin A/C.
Pubmed
14607793
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.130172832920474
Year of publication
2004
Drugs