Annotation Detail

Information
Associated Genes
LMNA
Associated Variants
LMNA p.Arg190Trp (p.R190W) ( ENST00000368301.6, ENST00000368300.9, ENST00000368297.5, ENST00000368299.7, ENST00000448611.6, ENST00000504687.7, ENST00000473598.6, ENST00000361308.9, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
LMNA p.Arg190Trp (p.R190W) ( ENST00000361308.9, ENST00000368297.5, ENST00000368299.7, ENST00000368300.9, ENST00000368301.6, ENST00000448611.6, ENST00000473598.6, ENST00000504687.7, ENST00000675667.1, ENST00000675939.1, ENST00000676385.2, ENST00000677389.1, ENST00000682650.1, ENST00000683032.1 )
Associated Disease
Left Ventricular Hypertrophy
Source Database
DisGeNET
Description
We described an asymptomatic 28-year-old man with a R190W lamin A/C gene mutation and mild left ventricular enlargement and near normal left ventricular ejection fraction who suffered from sudden cardiac death during sleeping.
Pubmed
17442430
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2008
Drugs