Annotation Detail

Information
Associated Genes
SETD1A
Associated Variants
SETD1A MUTATION
SETD1A MUTATION
Associated Disease
Neurodevelopmental Disorders
Source Database
DisGeNET
Description
We describe four H3K4me methyltransferases (KMT2A, KMT2C, KMT2D, KMT2F), four demethylases (KDM1A, KDM5A, KDM5B, KDM5C), and two reader proteins (PHF21A, PHF8) mutated in neurodevelopmental disorders.
Pubmed
26077434
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs