Annotation Detail
Information
- Associated Genes
- GRN
- Associated Variants
-
GRN c.*78C>T
(
ENST00000589265.5,
ENST00000053867.8 )
GRN c.*78C>T ( ENST00000053867.8, ENST00000589265.5 ) - Associated Disease
- dementia
- Source Database
- DisGeNET
- Description
- This is consistent with the finding that miR-659 binding to the high risk T allele of rs5848 may augment translational inhibition of GRN and alter risk of FTD and possibly other dementias.
- Pubmed
- 21047645
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.194317412339583
- Year of publication
- 2011
Drugs