Annotation Detail

Information
Associated Genes
MRC1
Associated Variants
MRC1 MUTATION
MRC1 MUTATION
Associated Disease
colorectal cancer
Source Database
DisGeNET
Description
Lynch syndrome is the most common form of hereditary colorectal cancer and is caused by germline mutations in the mismatch repair (MMR) genes MLH1, MSH2, MSH6 and PMS2.
Pubmed
25133505
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.0414546615581657
Drugs