Annotation Detail
Information
- Associated Genes
- ABO
- Associated Variants
-
ADAMTS7 SNV
ADAMTS7 SNV - Associated Disease
- Acute coronary syndrome
- Source Database
- DisGeNET
- Description
- C-allele carriers of the rs579459 variant, which is located upstream of the ABO gene and correlates with blood group A, were independently associated with recurrent MI [multivariable-adjusted hazard ratio (HR) 2.25, CI = 1.37-3.71; P = 0.001] and with recurrent MI or cardiac death [multivariable-adjusted (HR) 1.80, CI = 1.09-2.95; P = 0.021] within 5 years after an index ACS.
- Pubmed
- 23161703
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2013
Drugs