Annotation Detail

Information
Associated Genes
CHRNA5
Associated Variants
CHRNA5 c.*393T>C ( ENST00000299565.9, ENST00000348639.7 )
CHRNA3 c.*546C>T ( ENST00000348639.7, ENST00000326828.6 )
CHRNA5 c.*393T>C ( ENST00000348639.7, ENST00000299565.9 )
CHRNA3 c.*546C>T ( ENST00000326828.6, ENST00000348639.7 )
Associated Disease
Alcoholic Intoxication, Chronic
Source Database
DisGeNET
Description
We also observed two SNPs associated with alcohol dependence, that is, rs615470 in CHRNA5 (OR=0.77, P=0.0006) and rs578776 (OR=0.78, P=0.001).
Pubmed
20485328
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.132649485509251
Year of publication
2010
Drugs