Annotation Detail
Information
- Associated Genes
- MSH6
- Associated Variants
-
MSH6 MUTATION
MSH6 MUTATION - Associated Disease
- colorectal cancer
- Source Database
- DisGeNET
- Description
- Validation cohort: FFPE samples from 154 patients with primary stage III CRC (originally included in the RANX05 study) were classified according to MMR status by immunohistochemical analysis using validated antibodies for MLH1, MLH2, MSH6 and PMS2, and information on TOP1, CEN20, TOP2A and CEN17 status was previously published for this cohort.
- Pubmed
- 25777966
- Section of the abstract supporting the evidence
- MATERIAL AND METHODS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.101986791638505
Drugs