Annotation Detail
Information
- Associated Genes
- TXNRD2
- Associated Variants
-
TXNRD2 p.Ala66Ser (p.A66S)
(
ENST00000334363.14,
ENST00000400518.5,
ENST00000400519.6,
ENST00000400521.7,
ENST00000400525.6,
ENST00000491939.6,
ENST00000542719.6 )
TXNRD2 p.Ala66Ser (p.A66S) ( ENST00000334363.14, ENST00000400518.5, ENST00000400519.6, ENST00000400521.7, ENST00000400525.6, ENST00000491939.6, ENST00000542719.6 ) - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- For TXNRD2 A66S [AS versus AA: odds ratio (OR), 1.05; 95% confidence intervals (95% CI), 0.96-1.15; SS versus AA: OR, 1.12; 95% CI, 0.98-1.29], there are bioinformatics data to suggest that it is functional but confirmation in independent data sets is required before they can be regarded as definitive breast cancer susceptibility alleles.
- Pubmed
- 16424062
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00162865123248182
- Year of publication
- 2006
Drugs