Annotation Detail

Information
Associated Genes
TLR1
Associated Variants
TLR1 p.Ser602Ile (p.S602I) ( ENST00000308979.7, ENST00000502213.6 )
TLR1 p.Ser602Ile (p.S602I) ( ENST00000308979.7, ENST00000502213.6 )
Associated Disease
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site
Source Database
DisGeNET
Description
TLR1 1805T/G showed statistical differences when the control (Hp-) and infected (Hp+) groups (P = 0.041*) were compared; the TLR1 1805G allele had a protective effect towards infection (OR = 0.1; 95% CI = 0.01-0.88, P = 0.033*).
Pubmed
24754375
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2014
Drugs