Annotation Detail

Information
Associated Genes
CFTR
Associated Variants
SCNN1A p.Trp552Arg (p.W552R) ( ENST00000540037.5, ENST00000396966.6, ENST00000228916.7, ENST00000543768.1, ENST00000360168.7 )
SCNN1A p.Trp552Arg (p.W552R) ( ENST00000228916.7, ENST00000360168.7, ENST00000396966.6, ENST00000540037.5, ENST00000543768.1 )
Associated Disease
Intestinal Diseases
Source Database
DisGeNET
Description
p.W493R-SCNN1A was detected in three female carriers of F508del CFTR who did not show any symptoms of respiratory or intestinal disease that could be interpreted as the manifestation of CF or CFTR-related disorder.
Pubmed
21917531
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2012
Drugs