Annotation Detail

Information
Associated Genes
BTK
Associated Variants
BTK MUTATION
BTK MUTATION
Associated Disease
Xenograft Model
Source Database
DisGeNET
Description
Simultaneous inhibition of BTK and mTOR causes apoptosis both in vitro and in vivo and results in tumor regression in a xenograft model.
Pubmed
24970801
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs