Annotation Detail

Information
Associated Genes
CYP1B1
Associated Variants
CYP1B1 MUTATION
CYP1B1 MUTATION
Associated Disease
Xenograft Model
Source Database
DisGeNET
Description
Finally, we used proliferation and toxicity assays, as well as a mouse xenograft model using nude mice to determine whether α-naphthoflavone (ANF), a CYP1B1 specific inhibitor, reduces resistance to PTX.
Pubmed
25516145
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs