Annotation Detail
Information
- Associated Genes
- EPHX1
- Associated Variants
-
SULT1A1 p.Arg213His (p.R213H)
(
ENST00000569554.5,
ENST00000314752.12 )
EPHX1 p.Tyr113His (p.Y113H) ( ENST00000614058.4, ENST00000272167.10, ENST00000366837.5 )
SULT1A1 p.Arg213His (p.R213H) ( ENST00000314752.12, ENST00000569554.5 )
EPHX1 p.Tyr113His (p.Y113H) ( ENST00000272167.10, ENST00000366837.5, ENST00000614058.4 ) - Associated Disease
- Malignant neoplasm of lung
- Source Database
- DisGeNET
- Description
- MDR analysis identified two distinct predictor models for the risk of lung cancer in smokers (tobacco chewing, EPHX1 Tyr113His, and SULT1A1 Arg213His) and non-smokers (CYP1A1*2A, GSTP1 Ile105Val and SULT1A1 Arg213His) with testing balance accuracy (TBA) of 0.6436 and 0.6677 respectively.
- Pubmed
- 22206016
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0660377911371791
- Year of publication
- 2011
Drugs