Annotation Detail

Information
Associated Genes
CTLA4
Associated Variants
CTLA4 MUTATION
CTLA4 MUTATION
Associated Disease
Tumor Immunity
Source Database
DisGeNET
Description
Importantly, blocking coinhibitory molecules using antibodies specific for CTLA-4 and PD-1 enhances tumor immunity in a subset of patients.
Pubmed
25527357
Section of the abstract supporting the evidence
ALL_TEXT_1/3
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
2
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00217153497664243
Drugs