Annotation Detail
Information
- Associated Genes
- IL10RB
- Associated Variants
-
IL10RB MUTATION
IL10RB MUTATION - Associated Disease
- Tumor Immunity
- Source Database
- DisGeNET
- Description
- Our results suggest that mutations that disrupt the interactions of IL-10 with its receptors (IL-10RA and IL-10RB) and α2-macroglobulin (A2M) may enhance inflammation and modulate anti-tumor immunity.
- Pubmed
- 25056661
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 12
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs