Annotation Detail

Information
Associated Genes
MET
Associated Variants
MET p.Thr1010Ile (p.T1010I) ( ENST00000318493.11, ENST00000397752.8 )
MET p.Thr1010Ile (p.T1010I) ( ENST00000318493.11, ENST00000397752.8 )
Associated Disease
Thyroid carcinoma
Source Database
DisGeNET
Description
A missense MET sequence alteration T1010I, located in exon 14 encoding for the juxtamembrane domain of MET, was found in 6 (6%) of the 104 thyroid carcinomas examined, whereas all 92 goiter samples had wild-type exon 14 (P = 0.031).
Pubmed
15767811
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Year of publication
2005
Drugs