Annotation Detail
Information
- Associated Genes
- IL6
- Associated Variants
-
MET p.Thr1010Ile (p.T1010I)
(
ENST00000318493.11,
ENST00000397752.8 )
MET p.Thr1010Ile (p.T1010I) ( ENST00000318493.11, ENST00000397752.8 ) - Associated Disease
- Carcinoma breast stage IV
- Source Database
- DisGeNET
- Description
- The HGF growth factor receptor MET is potentially functionally altered due to an uncommon germline single nucleotide polymorphism (SNP), MET-T1010I, in many cancer lineages including breast cancer where the MET-T1010I SNP is present in 2% of patients with metastatic breast cancer.
- Pubmed
- 25605252
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
- Year of publication
- 2014
Drugs