Annotation Detail

Information
Associated Genes
HLA-DQB1
Associated Variants
ICAM1 p.Lys469Glu (p.K469E) ( ENST00000264832.8, ENST00000423829.2 )
ICAM1 p.Lys469Glu (p.K469E) ( ENST00000264832.8, ENST00000423829.2 )
Associated Disease
Diabetes Mellitus, Insulin-Dependent
Source Database
DisGeNET
Description
Linkage and association was not found between the ICAM-1 K469E variation and type 1 diabetes in Danish patients (P(tdt)> or =0.48), and our data did not indicate an interaction between ICAM1 and IDDM1 in predisposition to type 1 diabetes in Danes (P=0.78).
Pubmed
11132145
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.249975099027768
Year of publication
2000
Drugs