Annotation Detail

Information
Associated Genes
GNB3
Associated Variants
GNB3 p.Ser275= (p.S275=) ( ENST00000435982.6, ENST00000229264.8, ENST00000422785.7 )
GNB3 p.Ser275= (p.S275=) ( ENST00000229264.8, ENST00000435982.6, ENST00000422785.7 )
Associated Disease
Metabolic syndrome X
Source Database
DisGeNET
Description
The C825T polymorphism in the gene coding for the beta3 subunit of G proteins (GNB3) has been shown to be associated with several phenotypes such as hypertension, obesity, and diabetes mellitus comprising the metabolic syndrome.
Pubmed
15033462
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00900118904036822
Year of publication
2004
Drugs