Annotation Detail
Information
- Associated Genes
- CHRNA5
- Associated Variants
-
CHRNA3 p.Tyr215= (p.Y215=)
(
ENST00000348639.7,
ENST00000326828.6 )
rs1451240
CHRNB3 c.53-4274G>A ( ENST00000289957.3 )
CHRNA3 p.Tyr215= (p.Y215=) ( ENST00000326828.6, ENST00000348639.7 )
rs1451240
CHRNB3 c.53-4274G>A ( ENST00000289957.3 ) - Associated Disease
- cannabis abuse
- Source Database
- DisGeNET
- Description
- Rs16969968 in CHRNA5 (and its proxy, rs1051730 in CHRNA3) and rs1451240, a proxy for rs13280604 in CHRNB3, were associated with CPD after Bonferroni correction (p<0.006). rs1451240 was also associated with DSM-IV cannabis abuse/dependence.
- Pubmed
- 25770649
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2015
Drugs