Annotation Detail
Information
- Associated Genes
- CYP11B2
- Associated Variants
-
GNB3 p.Ser275= (p.S275=)
(
ENST00000435982.6,
ENST00000229264.8,
ENST00000422785.7 )
CYP11B2 p.Tyr275= (p.Y275=) ( ENST00000323110.2 )
GNB3 p.Ser275= (p.S275=) ( ENST00000229264.8, ENST00000435982.6, ENST00000422785.7 )
CYP11B2 p.Tyr275= (p.Y275=) ( ENST00000323110.2 ) - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- In addition to these polymorphisms, the T(-344)C polymorphism in the promoter of the aldosterone synthase gene (CYP11B2) and the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) are considered candidates for the genetic risk of salt-sensitive hypertension.
- Pubmed
- 12924618
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.143123487147592
- Year of publication
- 2003
Drugs