Annotation Detail
Information
- Associated Genes
- PTGS2
- Associated Variants
-
PTGS2 c.*427T>C
(
ENST00000680451.1,
ENST00000367468.10 )
PTGS2 c.*427T>C ( ENST00000367468.10, ENST00000680451.1 ) - Associated Disease
- Malignant neoplasm of ovary
- Source Database
- DisGeNET
- Description
- In a pooled analysis of two population-based studies, the Hawaii Ovarian Cancer Case-Control Study and the New England Case-Control Study, including 1,025 women with invasive ovarian carcinoma and 1,687 cancer-free controls, the association of ovarian cancer risk with the PTGS2 rs5275 polymorphism and the use of nonsteroidal antiinflammatory drugs (NSAIDs) were examined.
- Pubmed
- 20559705
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00969596252477022
- Year of publication
- 2010
Drugs