Annotation Detail
Information
- Associated Genes
- PPARG
- Associated Variants
-
PPARG MUTATION
PPARG MUTATION - Associated Disease
- Mammary Neoplasms
- Source Database
- DisGeNET
- Description
- We conclude that the interaction between IGFBP-3 and PPARγ is important for the growth-inhibitory effect of PPARγ ligands in human breast cancer cells, suggesting that IGFBP-3 expression by breast tumors may regulate their sensitivity toward PPARγ ligands.
- Pubmed
- 25449421
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,LHGDN
- DisGENET score for the Gene Disease association
- 0.022337685683898
Drugs