Annotation Detail
Information
- Associated Genes
- HYKK
- Associated Variants
-
HYKK c.478-5676G>A
(
ENST00000388988.9,
ENST00000566332.5,
ENST00000569878.5 )
rs2036527
CHRNA3 p.Tyr215= (p.Y215=) ( ENST00000348639.7, ENST00000326828.6 )
HYKK c.478-5676G>A ( ENST00000388988.9, ENST00000566332.5, ENST00000569878.5 )
rs2036527
CHRNA3 p.Tyr215= (p.Y215=) ( ENST00000326828.6, ENST00000348639.7 ) - Associated Disease
- Carcinoma of lung
- Source Database
- DisGeNET
- Description
- Associations of SNPs in LOC123688 (rs10519203; odds ratio [OR] = 1.60, 95% confidence interval [CI] = 1.25 to 2.05, P = .00016), CHRNA5 (rs2036527; OR = 1.67, 95% CI = 1.26 to 2.21, P = .00031), and CHRNA3 (rs1051730; OR = 1.81, 95% CI = 1.26 to 2.59, P = .00137) genes with lung cancer risk reached Bonferroni-corrected levels of statistical significance (all statistical tests were two-sided).
- Pubmed
- 20554942
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
- Year of publication
- 2010
Drugs