Annotation Detail

Information
Associated Genes
CHRNA3
Associated Variants
CHRNA3 p.Tyr215= (p.Y215=) ( ENST00000348639.7, ENST00000326828.6 )
CHRNA3 c.378-1523T>C ( ENST00000326828.6, ENST00000348639.7 )
CHRNA3 p.Tyr215= (p.Y215=) ( ENST00000326828.6, ENST00000348639.7 )
CHRNA3 c.378-1523T>C ( ENST00000326828.6, ENST00000348639.7 )
Associated Disease
Drug habituation
Source Database
DisGeNET
Description
We, therefore, investigated the impact of two common CHRNA3 polymorphisms (rs1051730/rs1317286) on PPI, startle reactivity, and habituation of the ASR in two independent samples of 107 healthy British volunteers and 73 schizophrenia patients hailing from Germany.
Pubmed
20393456
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2010
Drugs