Annotation Detail

Information
Associated Genes
CHRNA3
Associated Variants
HYKK c.337+256T>C ( ENST00000569878.5, ENST00000566332.5, ENST00000388988.9 )
CHRNA3 p.Tyr215= (p.Y215=) ( ENST00000348639.7, ENST00000326828.6 )
HYKK c.337+256T>C ( ENST00000388988.9, ENST00000566332.5, ENST00000569878.5 )
CHRNA3 p.Tyr215= (p.Y215=) ( ENST00000326828.6, ENST00000348639.7 )
Associated Disease
nicotine dependence
Source Database
DisGeNET
Description
Genotypes for two SNPs in the CHRNA3/5 region (rs8034191, rs1051730) previously associated with nicotine dependence and COPD were analyzed for association to COPD and nicotine dependence phenotypes.
Pubmed
21232152
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.133420203863774
Year of publication
2011
Drugs